Knowledge Exchange Newsletter, April 2016

Outbreak Watch

  • 14 cases of typhoid fever were reported in Tailevu province, Fiji, at the end of March. More cases were reported throughout Fiji in April; the increase in typhoid was linked to the damage caused by tropical cyclone Winston, which struck the country in late February.
  • Typhoid claimed 6 lives in Masaka district, Uganda, in early April.
  • ​18 cases of typhoid fever were confirmed in Mchinji district, Malawi, in mid-April, prompting local hospitals to hold educational meetings on hygiene practices.


Diagnostics and Treatments

Epidemiology and Surveillance

Genomics and Host Susceptibility

  • Functional Activity of Antibodies Directed towards Flagellin Proteins of Non-Typhoidal Salmonella – PLoS One
  • Genotyping of Salmonella Typhi using 8-loci multi locus VNTR analysis – Gut Pathogens 
  • The Typhoid Toxin Promotes Host Survival and the Establishment of a Persistent Asymptomatic Infection – PLoS Pathogens


  • Status of paratyphoid fever vaccine research and development – Vaccine


Photo Credit: UNICEF

Photo Credit: Yannis Guibinga