Knowledge Exchange Newsletter, January/February 2017

​​Stories of Typhoid: Asim

Meet Asim. In his low-income urban neighborhood in Pakistan, it can seem as if the one thing more widespread than typhoid is misinformation about typhoid. Crucial information on the prevention of the disease through handwashing, drinking clean water or receiving a vaccination is often missing in places where typhoid is endemic, leaving kids like Asim at high risk of suffering unnecessarily from preventable diseases.

Until recently, Asim didn’t know much more about typhoid than any other kid from his neighborhood. He didn’t know that typhoid is transmitted through contaminated food and water, or that some street vendors can’t guarantee the safety of the food they’re selling. Asim didn’t know that every time he bought his favorite snacks from the street vendor near his school, he ran the risk of contracting typhoid. But one day that risk caught up with him. Read more about his story.

Conference Updates

The 10th International Conference on Typhoid and Other Invasive Salmonelloses is fast approaching. Don’t forget to register before the March 6 deadline.

The conference program overview is now up on our website, where you can also find important conference dates and travel information. We hope to see you all April 4-6, 2017, in Uganda.

From the Blog

  • Looking Back at 2016 – As the past year has come to a close, our team at the Coalition against Typhoid would like to take a moment to reflect on this busy year
  • Recurring Typhoid Nightmare in Zimbabwe – After struggling with outbreaks for more than a year, Zimbabwe is facing yet another deadly wave of typhoid as it begins the new year

Outbreak Watch


Featured: Typhoid Fever Surveillance in Africa Project

  • Typhoid in Africa and vaccine deployment – Lancet Global Health
  • Incidence of invasive salmonella disease in sub-Saharan Africa: a multicentre population-based surveillance study – Lancet Global Health

Case Report/Clinical Outcome

Diagnostics and Treatment


  • A Large and Persistent Outbreak of Typhoid Fever Caused by Consuming Contaminated Water and Street-Vended Beverages: Kampala, Uganda, January-June 2015 – BMC Public Health
  • Poverty-related Diseases (PRDs): Unravelling Complexities in Disease Responses in Cameroon – Tropical Medicine and Health
  • Application of landscape epidemiology to assess potential public health risk due to poor sanitation – Journal of Environmental Management


  • The Cytolethal Distending Toxin Produced by Nontyphoidal Salmonella Serotypes Javiana, Montevideo, Oranienburg, and Mississippi Induces DNA Damage in a Manner Similar to That of Serotype Typhi – mBio


  • Whole Genome Sequence Analysis of Salmonella Typhi Isolated in Thailand Before and After the Introduction of a National Immunization Program – PLoS Neglected Tropical Diseases
  • Evaluation of the clinical and microbiological response to Salmonella Paratyphi A infection in the first paratyphoid human challenge model – Clinical Infectious Diseases
  • Salmonella Typhi Lipopolysaccharide O-antigen Modifications Impact on Serum Resistance and Antibody Recognition – Infection and Immunity
  • Modeling the Potential for Vaccination to Diminish the Burden of Invasive Non-typhoidal Salmonella Disease in Young Children in Mali, West Africa – PLoS Neglected Tropical Diseases

Water, Sanitation and Hygiene

  • Food Safety Knowledge, Attitudes and Practices of Institutional Food-Handlers in Ghana – BMC Public Health


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