Knowledge Exchange Newsletter, May 2016

Dear Member,

The Coalition against Typhoid is excited to announce Stories of Typhoid, a series of profiles sharing the impact of typhoid on families in endemic countries. In the inaugural profile, we meet Rasmina, a 5 year old from Banepa, Nepal who contracted typhoid earlier this year.


Stories of Typhoid will publish a new profile every month with stories from typhoid-affected families in Asia and Africa. Through these profiles, we will go beyond the statistics to get to know the real people impacted by typhoid.

We hope you enjoy reading Stories of Typhoid, and share it with your colleagues and friends.



Denise Garrett, MD, MS
Director, Coalition against Typhoid (CaT) Secretariat
Vaccine Advocacy and Education
Sabin Vaccine Institute

Outbreak Watch

  • Guests at a wedding reception in Kunnathuparamba, Nediyiruppu, in the Kondotty municipal limits, were infected with typhoid fever in late March.
  • Also in India, cases of typhoid have increased in Chennai. Chicken pox and acute diarrheal disease are also on the rise.


Diagnostics and Treatments

Epidemiology and Surveillance

Genomics and Host Susceptibility

  • Dynamic Duo – The Salmonella Cytolethal Distending Toxin Combines ADP-Ribosyltransferase and Nuclease Activities in a Novel Form of the Cytolethal Distending Toxin – Toxins
  • Emergence of blaCTX-M-15, blaTEM-169 and blaPER-1 extended-spectrum β-lactamase genes among different Salmonella enterica serovars from human faecal samples – Infectious Diseases