Tag: drug-resistant typhoid

Vaccines can protect against drug-resistant typhoid

We can’t stop drug-resistant typhoid without vaccines

Posted on February 7, 2022 by Joseph Walker, Dr. Ruthie Birger, and Dr. Virginia Pitzer, Yale School of Public Health

For an increasing number of communities, typhoid is a real and dangerous threat. Symptoms can last for weeks or months, keeping children out of school and preventing families from earning ...

Lab worker sequences typhoid isolates in India.

Drug-resistant typhoid in India

Posted on November 24, 2021 by Silvia Argimón, Center for Genomic Pathogen Surveillance

Drug resistance occurs when a pathogen—whether bacteria, virus, or fungus—evolves to withstand the drug that is given for treatment. Drug resistance is a top health concern identified by the World ...

Has drug-resistant typhoid reached Latin America? Genetic evidence from Colombia

Posted on September 22, 2021 by Laura Kallen

Photo: Panoramic view, Medellin, Antioquia, Colombia. The Antioquia Health Department has seen a high rate of typhoid cases, mainly in the geographic region of Uraba. Drug-resistant typhoid is a rising ...

Family with a vaccinator during the drug-resistant typhoid outbreak response campaign

Typhoid conjugate vaccine is effective against drug-resistant typhoid

Posted on September 9, 2021 by Dr. Farah Naz Qamar, Aga Khan University, Pakistan

A recently published study from Hyderabad, Pakistan, shows that typhoid conjugate vaccine (TCV) is highly effective against drug-resistant typhoid. This is exciting and reassuring data as multidrug- and extensively drug-resistant ...

Animated gif showing usage of the Pathogenwatch platform

An app for Typhi genomes

Posted on June 28, 2021 by Silvia Argimón

Note: This blog originally appeared on the Nature Portfolio Microbiology Community. Typhoid fever is a serious enteric disease spread through food and water contaminated with Salmonella enterica serovar Typhi (S. Typhi). In 2017, ...

Informal settlement in Chandigarh, India

Azithromycin-resistant typhoid in Chandigarh signals urgent need for typhoid conjugate vaccine introduction

Posted on February 8, 2021 by Ruby Jain, Megan Carey, Kanwaljeet S. Sandha, and Neelam Taneja

Photo: Temporary workers living in informal settlements in Chardigarh, India, often face limited access to clean water and sanitation, putting them at high risk for typhoid. Typhoid fever, which ...

At ASTMH, more evidence that TCVs work – and just in time

Posted on November 25, 2020 by Laura Kallen, PATH

Photo: A boy receives typhoid conjugate vaccine (TCV) in Sindh Province, Pakistan, during the campaign in 2019. TCVs are a promising tool to combat rising rates of drug-resistant typhoid. Like ...

One step closer to untreatable typhoid

Posted on November 19, 2020 by Megan E. Carey, Cambridge Institute of Therapeutic Immunology & Infectious Disease, Department of Medicine, University of Cambridge, Cambridge, UK; Yogesh Hooda, Child Health Research Foundation, Department of Microbiology, Dhaka Shishu Hospital, Dhaka, Bangladesh; Junaid Iqbal, Department of Paediatrics and Child Health, Aga Khan University, Karachi, Pakistan; Abhilasha Karkey, Oxford University Clinical Research Unit, Patan Academy of Health Sciences, Kathmandu, Nepal; Ruby Jain, Civil Hospital, Manimajra, Chandigarh, India; Denise O. Garrett, Sabin Vaccine Institute, Washington, DC, USA; Duy Pham Thanh, Oxford University Clinical Research Unit-Vietnam; Neelam Taneja, Department of Medical Microbiology, Postgraduate Institute of Medical Education and Research, Chandigarh, India; Farah Qamar, Department of Paediatrics and Child Health, Aga Khan University, Karachi, Pakistan; Senjuti Saha, Child Health Research Foundation, Dhaka, Bangladesh; Stephen Baker, Cambridge Institute of Therapeutic Immunology & Infectious Disease, Department of Medicine, University of Cambridge, Cambridge, UK

This post was originally posted on the Gavi #VaccinesWork blog. Typhoid, the infectious disease caused by the bacterium Salmonella Typhi (S. Typhi), is spread through contaminated food and water and ...

Another piece of the puzzle: Using genomic data to understand typhoid burden

Posted on July 16, 2020 by Megan E. Carey and Stephen G. Baker, Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID), Department of Medicine, University of Cambridge

This blog is part of a broader series on drug resistance and its increasing threat to global health. For policymakers, prioritization of vaccines for routine immunization programs is a critical ...

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