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Estimation of the probability of bacterial population survival: Development of a probability model to describe the variability in time to inactivation of Salmonella enterica

by admin July 19, 2017
AUTHORS Kento Koyama, Hidekazu Hokunan, Mayumi Hasegawa, Shigenobu Koseki ABSTRACT Despite the development of numerous predictive microbial inactivation models, a model focusing on the variability in time to inactivation for a bacterial population has not been developed. Additionally, an appropriate estimation of the risk of there being any remaining bacterial survivors in foods after the [...] readmore

Gallbladder sludge associated with ceftriaxone therapy for typhoid fever in Nigerian children: A case series

by admin July 19, 2017
AUTHORS Hafsatu W Idris, Lawal W Umar, Sakina Abdullahi, Ahmed U Hamidu ABSTRACT Ceftriaxone is a third-generation cephalosporin with a wide spectrum of activity against both gram-negative and gram-positive organisms. Ceftriaxone has proven efficacy against severe and difficult-to-treat community-acquired infections including typhoid fever and other sepsis syndromes caused by multi-drug [...] readmore

Population-based incidence, seasonality and serotype distribution of invasive salmonellosis among children in Nanoro, rural Burkina Faso

by admin July 12, 2017
AUTHORS Guiraud I, Post A, Diallo SN, Lompo P, Maltha J, Thriemer K, Tahita CM, Ley B, Derra K, Bottieau E, Kazienga A, Schurmans C, Ravinetto R, Rouamba E, Van Griensven J, Bertrand S, Tinto H, Jacobs J ABSTRACT BACKGROUND: Bloodstream infections (BSI) caused by Salmonella Typhi and invasive non-Typhoidal Salmonella (iNTS) frequently affect children living in rural sub-Saharan Africa but [...] readmore

DEATH AND THE MEDIA: INFECTIOUS DISEASE REPORTING DURING THE HEALTH TRANSITION

by admin July 12, 2017
AUTHORS Costa DL, Kahn ME ABSTRACT In the late 19th Century, cities in Western Europe and the United States suffered from high levels of infectious disease. Over a 40 year period, there was a dramatic decline in infectious disease deaths in cities. As such objective progress in urban quality of life took place, how did the media report this trend? At that time newspapers were the major source [...] readmore

Chronic active parietal osteomyelitis due to Salmonella typhi in a patient with Sickle Cell Anemia

by admin July 12, 2017
AUTHORS Ahmad Antar, George Karam, Maurice Kfoury, Nadim El- Majzoub ABSTRACT Sickle cell disease (SCD) is a genetic disorder characterized by a marked heterogeneity in clinical and hematologic severity, with musculoskeletal system manifestations being a major cause of morbidity and disability. The increased susceptibility of SCD patients to infections, including osteomyelitis, has long been [...] readmore

Molecular Subtyping of Salmonella enterica Serovar Typhi by Pulsed-Field Gel Electrophoresis and Multiple-Locus Variable-Number Tandem-Repeat Analysis in India: Their Association with Antimicrobial Resistance Profiles

by admin July 5, 2017
AUTHORS Das S, Samajpati S, Roy I, Sankar S, Gaind R, Deb M, Kulkarni R, Kumar Paul D, Dutta S ABSTRACT Molecular subtyping, and recently DNA sequencing based methods, which are commonly used for discriminating Salmonella enterica serovar Typhi (S. Typhi) isolates, leads to improved molecular epidemiological investigations for prevention and control of typhoid fever. We included S. Typhi [...] readmore

The STRATAA study protocol: a programme to assess the burden of enteric fever in Bangladesh, Malawi and Nepal using prospective population census, passive surveillance, serological studies and healthcare utilisation surveys

by admin July 5, 2017
AUTHORS Darton TC, Meiring JE, Tonks S, Khan MA, Khanam F, Shakya M, Thindwa D, Baker S, Basnyat B, Clemens JD, Dougan G, Dolecek C, Dunstan SJ, Gordon MA, Heyderman RS, Holt KE, Pitzer VE, Qadri F, Zaman K, Pollard AJ; STRATAA Study Consortium ABSTRACT INTRODUCTION: Invasive infections caused by Salmonella enterica serovar Typhi and Paratyphi A are estimated to account for 12-27 million [...] readmore

Specific and cross-reactive plasmablast response in humans after primary and secondary immunization with Vi capsular polysaccharide typhoid vaccine

by admin July 5, 2017
AUTHORS Pakkanen SH, Kantele JM, Rombo L, Kantele A ABSTRACT Secondary immunization with polysaccharide vaccines may imply a risk of hyporesponsiveness. Despite the wide use of typhoid Vi capsular polysaccharide vaccine, its potential tendency to hyporesponsiveness has been inadequately addressed. While previous studies have explored serum antibody responses, we applied a more sensitive [...] readmore

Clean water, clean hands or new vaccines?

by admin June 28, 2017
AUTHORS Stephen P. Luby ABSTRACT Throughout human history, pathogens transmitted through feces from person to person have caused substantial mortality. Over a century ago civil engineers in high income countries developed approaches to collect and remove feces from the environment that in communities with high incomes and strong governments markedly reduced the burden of enteric disease. [...] readmore

Development of ELISAs for diagnosis of acute typhoid fever in Nigerian children

by admin June 28, 2017
AUTHORS Jiin Felgner, Aarti Jain, Rie Nakajima, Li Liang, Algis Jasinskas, Eduardo Gotuzzo, Joseph M. Vinetz, Fabio Miyajima, Munir Pirmohamed, Fatimah Hassan-Hanga, Dominic Umoru, Binta Wudil Jibir, Safiya Gambo, Kudirat Olateju, Philip L. Felgner, Stephen Obaro ABSTRACT Improved serodiagnostic tests for typhoid fever (TF) are needed for surveillance, to facilitate patient management, curb [...] readmore
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