​Knowledge Exchange Newsletter, September 2016

​Stories of Typhoid: Meet Yadav

Meet Yadav. A 27-year-old lab assistant in Gurgaon, India, Yadav is remarkably conscientious about avoiding diseases transmitted through contaminated food and water. He cooks at home to avoid eating food bought on the street, where the risk of transmission is much higher. He drinks filtered water, and washes his hands with soap on a regular basis. Yet Yadav’s precautions could not totally overcome the risks of life in his village, which is plagued by water and sewage problems.

So despite his precautions, Yadav fell ill with typhoid. The classic symptoms hit him with full force; a high fever, constant nausea, bouts of vomiting and worst of all, body aches and fatigue. “I couldn’t sleep at night,” said Yadav. “It was very hard on me.” Read more about his story.

Save the Date

The 10th International Conference on Typhoid and Other Invasive Salmonelloses will be held in Kampala, Uganda, from April 4-6, 2017. Abstract and symposium submissions are open now and close October 28. Head to our website for submission guidelines and more conference information. Help us promote the conference, encourage diverse participation from across the world, and let your network know where you’ll be in April with our Social Media Toolkit!

Join us at the American Society for Tropical Medicine and Hygiene Annual Meeting

  • November 14 from 4:00 PM – 5:45 PM: Bridging the Gap Towards Defining the Burden of Typhoid in Sub-Saharan Africa and Southeast Asia. Symposium #45.
  • November 15 from 4:00 PM – 6:00 PM: Typhoid, Paratyphoid and Invasive Non-Typhoidal Salmonella: A Time for Action. Side event in room 205 at the Hilton Atlanta. Contact us for more information.

Outbreak Watch

​The Dirt on Water

  • Asia, Africa, and Latin America – a report by the UN Environment Programme warns that a worrying rise in pathogen pollution in surface waters could put up to 323 million people at risk of infection.
  • India – Illegal access to water pipelines from unauthorized colonies on the outskirts of Gurgaon has contaminated the water supply so that 15 percent of the homes in Gurgaon are now receiving water that is not safe for drinking.

Waste Not



  • Using a Human Challenge Model of Infection to Measure Vaccine Efficacy: A Randomised, Controlled Trial Comparing the Typhoid Vaccines M01ZH09 with Placebo and Ty21a – PLOS Neglected Tropical Diseases

Antimicrobial Resistance

Diagnostics and Treatments

  • Bacteriophage​​ tailspike protein based assay to monitor phase variable glucosylations in Salmonella O-antigens – BMC Microbiology
  • A magneto-DNA nanoparticle system for the rapid and sensitive diagnosis of enteric fever – Scientific Reports


  • Health at the Sub-catchment Scale: Typhoid and Its Environmental Determinants in Central Division, Fiji – Ecohealth


Genomics and Host Susceptibility

  • Elevated Values of C-Reactive Protein Induced by Imported Infectious Diseases: A Controlled Cross-Sectional Study of 11,079 Diseased German Travelers Returning from the Tropics and Subtropics – The American Journal of Tropical Medicine and Hygiene
  • Distinct Salmonella Enteritidis lineages associated with enterocolitis in high-income settings and invasive disease in low-income settings – Nature Genetics

To contribute to the Coalition Against Typhoid Knowledge Exchange Newsletter, contact us at cat@sabin.org. Like us on Facebook and Twitter for frequent updates.

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