Tag: XDR typhoid

Four immunization campaign workers carry containers of typhoid conjugate vaccines down a street during a typhoid immunization campaign in Pakistan. A new study will investigate the potential of typhoid conjugate vaccines to reduce antimicrobial use.

The potential of typhoid conjugate vaccines to reduce antimicrobial use in Pakistan

Posted on March 26, 2025 by Dr. Megan E. Carey¹ ², Dr. Mohammad Tahir Yousafzai³, Dr. Muhammad Jawad³, Dr. Farah Naz Qamar³, Dr. James E. Meiring⁴ ⁵

Drug-resistant typhoid is a major public health challenge in Pakistan, where an estimated 25 percent of cases are extensively drug-resistant (XDR). In Pakistan’s Sindh and Punjab provinces, 65% and 44% ...

What the spread of extensively drug-resistant Salmonella Typhi tells us about future outbreaks

Posted on October 31, 2023 by Jo Walker, Yale

Drug-resistant typhoid is a growing concern as the number of cases resistant to one or more antibiotics is increasing globally. This suggests that existing antibiotics may not effectively treat typhoid. ...

Family with a vaccinator during the drug-resistant typhoid outbreak response campaign

Typhoid conjugate vaccine is effective against drug-resistant typhoid

Posted on September 9, 2021 by Dr. Farah Naz Qamar, Aga Khan University, Pakistan

A recently published study from Hyderabad, Pakistan, shows that typhoid conjugate vaccine (TCV) is highly effective against drug-resistant typhoid. This is exciting and reassuring data as multidrug- and extensively drug-resistant ...

The power of vaccines against drug-resistant typhoid

Posted on November 23, 2020 by Elayna Oberman, PATH

Every year in November, the global health community observes World Antibiotic Awareness Week to raise awareness about the growing threat of antimicrobial resistance and to encourage best practices among the ...

One step closer to untreatable typhoid

Posted on November 19, 2020 by Megan E. Carey, Cambridge Institute of Therapeutic Immunology & Infectious Disease, Department of Medicine, University of Cambridge, Cambridge, UK; Yogesh Hooda, Child Health Research Foundation, Department of Microbiology, Dhaka Shishu Hospital, Dhaka, Bangladesh; Junaid Iqbal, Department of Paediatrics and Child Health, Aga Khan University, Karachi, Pakistan; Abhilasha Karkey, Oxford University Clinical Research Unit, Patan Academy of Health Sciences, Kathmandu, Nepal; Ruby Jain, Civil Hospital, Manimajra, Chandigarh, India; Denise O. Garrett, Sabin Vaccine Institute, Washington, DC, USA; Duy Pham Thanh, Oxford University Clinical Research Unit-Vietnam; Neelam Taneja, Department of Medical Microbiology, Postgraduate Institute of Medical Education and Research, Chandigarh, India; Farah Qamar, Department of Paediatrics and Child Health, Aga Khan University, Karachi, Pakistan; Senjuti Saha, Child Health Research Foundation, Dhaka, Bangladesh; Stephen Baker, Cambridge Institute of Therapeutic Immunology & Infectious Disease, Department of Medicine, University of Cambridge, Cambridge, UK

This post was originally posted on the Gavi #VaccinesWork blog. Typhoid, the infectious disease caused by the bacterium Salmonella Typhi (S. Typhi), is spread through contaminated food and water and ...

People purchase medication at the Pharmacie Bakh Yaye in Thies, Senegal. PATH

Drug-resistant typhoid: How it became a global health crisis

Posted on March 12, 2019 by Zoe Dyson, University of Cambridge

The past century has witnessed remarkable global health progress. We have identified treatments and cures for diseases, we have developed vaccines to prevent some of the deadliest diseases, and for ...

How Pakistan’s new generation of disease hunters helped expose XDR typhoid

Posted on February 4, 2019 by Laura Kallen

The outbreak of extensively drug-resistant (XDR) typhoid in Pakistan has now been going on for more than two years. As is the case in most low- and middle-income countries, Pakistan ...