Global Research

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Typhoid fever remains a public health threat in many developing countries, despite being one of the first diseases for which a vaccine existed. Due to rapid urbanization without corresponding improvements in water and sanitation infrastructure, the global incidence of typhoid has increased dramatically.

Current global burden of disease estimates are based on limited studies conducted over the past 25 years. Most incidence estimates are based primarily on information collected from vaccine trials rather than studies focused on the surveillance of vaccine preventable disease such as typhoid; therefore, it is likely that the burden of typhoid has been underestimated.

The Coalition is leading research efforts to fill the data gap on typhoid and paratyphoid. Learn more about our current research underway here.

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