Typhoid News
Three-day 15th ASCODD kicks off in city Tuesday
- International, regional and national public health experts will gather in Dhaka on January 28-30 to discuss challenges and solutions of typhoid fever, cholera, malnutrition and other enteric diseases in low and middle-income countries in an era of humanitarian crisis
- Diarrhoeal diseases are still the third leading cause of child mortality globally
- An estimated 11–20 million people suffer from typhoid fever. In South Asia, typhoid fever is the most common bloodstream infection
Do studies underestimate the prevalence of typhoid?
- Blood culture surveillance programs are critical for estimating the prevalence of typhoid and paratyphoid fevers, but cases can be missed when patients don’t seek medical care, or seek medical care and don’t have a blood culture test
- The Typhoid Vaccine Acceleration Consortium (TyVAC), a partnership between the Center for Vaccine Development and Global Health at the University of Maryland School of Medicine, the Oxford Vaccine Group at the University of Oxford, and PATH, an international nonprofit, aims to accelerate the introduction of new typhoid conjugate vaccines (TCVs)
Daewoong launches oral typhoid fever vaccine
- Daewoong Pharmaceutical said that it has launched Vivotif, an oral typhoid fever vaccine, in the local market
- Vivotif is the only typhoid fever vaccine in Korea that received approval by the U.S. Food and Drug Administration and European Medicines Agency
- In a clinical study of 10,594 patients in Santiago, Chile, where typhoid fever was present, a single dose of Vivotif showed that it prevented typhoid fever in 71 percent of the patients in its first year, and 67 percent of the patients after three years
Zimbabwe: ‘Water, Sanitation Key to Ending Recurrent Diarrhoeal Diseases’
- Providing adequate safe water and improving sanitation is key to ending recurrent outbreaks of diarrhoeal diseases that include typhoid, cholera and common diarrhoea in Harare’s western suburbs
- Disease and epidemiology control director in the Ministry of Health and Child Care Dr Portia Manangazira said while Government rolled out cholera and typhoid vaccines last year to protect residents against water-borne diseases, improving the city’s water and sanitation remained critical
Six common diseases to watch out for during floods
- The torrential rains that caused massive floods in Greater Jakarta on New Year’s Eve may have subsided, but the rainy season is far from over, meaning more floods are likely
- Those affected by floods are at risk of getting infected with water-borne diseases contracted through direct contact with polluted waters. Floods also serve as a prime breeding site for mosquitoes, which also transmit many vector-borne diseases
- According to the World Health Organization (WHO), there are six diseases or health problems in particular that are worth looking out for during floods: typhoid fever, cholera, hepatitis A, malaria, dengue fever, and hypothermia
Typhoid vaccine Phase 3 trial in Nepal
- In Nepal, the typhoid conjugate vaccine has proven to be very effective in protecting against typhoid fever
- The typhoid antibody titers more than quadrupled in the participants that received the typhoid conjugate vaccine
Zac Efron contracted what’s believed to be typhoid fever while filming show in Papua New Guinea
- Zac Efron was hospitalized last week after contracting a bacterial infection, believed to be typhoid fever, in Papua New Guinea
- On Monday, he took to Twitter to say he had “bounced back” from the serious and potentially deadly illness
- Typhoid fever, which is believed to be the infection Efron had, is a potentially life-threatening illness caused by bacteria, according to the CDC
13 suspected typhoid cases hit Glen View
- Typhoid is still endemic in Harare’s Glen View high-density suburb, with another 13 suspected new cases recorded in recent weeks by the City Health Department
- Typhoid is not new to Glen View, where the last outbreak that hit the suburb at the beginning of this year claimed 49 lives, while over 10 000 people were treated and discharged
P&O liner typhoid victim Stuart Balfour from Deal recalls his ordeal 50 years on
- Little did Stuart Balfour know when he boarded the P&O liner Oronsay 50 years ago, that he would be subjecting himself to one of the most frightening experiences of his life
- The 20 year-old Deal lad had left school and dreamed of travelling the world as a fireman in the engine room of the vessel
- But that dream was shattered when he contracted typhoid and was forced into quarantine for five days before spending four weeks and a day in Vancouver General Hospital
A water purifier for remote areas
- Data by the Central Bureau of Health Intelligence (CBHI) and ministry of health and family welfare indicated that 2,439 persons died in India in 2018 due to water borne diseases – cholera, acute diarrhea, typhoid and viral hepatitis
- A team of researchers at IIT Gandhinagar (IIT-Gn) has prepared surface-engineered particles (SEP) to arrest bacteria from microbe contaminated water
Typhoid vaccine to be made part of routine immunisation programme
- Khyber Pakhtunkhwa has started preparations to include typhoid conjugate vaccine (TCV) in its routine immunisation programme as part of the government’s plan to protect people against the vaccine-preventable disease
- The WHO has issued formal recommendation in support of TCV’s introduction in March 2018 to put brakes on deaths caused by typhoid
- Dr Salim said that the Khyber Pakhtunkhwa government had planned to improve water and sanitation services in line with the federal government’s guideline to safeguard children against preventable ailments
Liberia Begins Preparation for Typhoid Vaccine
- Monrovia – Liberia has begun massively preparing to launch the typhoid conjugate Vaccine come early next year, according to information from the Ministry of Health
- According to the Health Ministry’s Communications Consultant, Mr. Sorbor George, topics for the preparation include Data Analysis, Problems Identifications, Vaccine Forecast, among others
- George stated that a study conducted by the Global Burden of Disease estimates that Liberia recorded over 7000 typhoid cases in 2017
Typhoid vaccine ‘works fantastically well’
- Experts said the vaccine was a game-changer and would reduce the “terrible toll wrought by typhoid”
- More than 20,000 children – aged from nine months to 16 years – in Kathmandu Valley, Nepal, took part in the trial
- Half of the children were given the vaccine and their cases of typhoid fell by 81% in the first year of the study
New typhoid fever vaccine protects young children
- The test in Nepal “provides the first evidence of the level of impact and the potential for improving the health of children in some of these very vulnerable populations around the world”
- The vaccine, known as TCV, has already been endorsed by the World Health Organization’s Global Advisory Committee on Vaccine Safety based in part on earlier tests at Oxford
Anti-typhoid vaccination drive continues
- The Typhoid Conjugate Vaccine (TCV) campaign resumed on Monday and will continue for another six days in Karachi with the aim to vaccinate the children who have been missed in the last round
- The authorities claimed to have covered more than 90% of the 10.1 million targeted children, aged between 9 months to 15 years
- Vaccinators and skilled lady health workers have been deployed for conducting outreach sessions in the community, whereas, EPI fixed centres are also administering the TCV to the children between 9am and 4pm
Salmonella Study at Michigan State University: Salmonella is Evolving
- A new study at Michigan State University (MSU) researched how salmonella is changing and, in particular, its resistance to antibiotics
- There are over two thousand strains of salmonella bacteria with around 100 strains connected to human infection – with myriad common strains from Salmonella Heidelberg to Salmonella Typhimurium to Salmonella Infantis
- In Michigan where the salmonella study was conducted, doctors are continually experiencing more cases where some strains of salmonella are resistant to antibiotics
Typhoid tops the health scare chart
- While the WHO has lauded Pakistan’s efforts to prevent the spread of typhiod, the global community is increasingly alarmed about the possibility of Pakistan becoming the hub for typhoid, just like it was for polio up until a few years ago
- According to the Global Burden of Disease study estimates, there were nearly 11 million typhoid cases and more than 116 000 typhoid deaths worldwide in 2017. And if left unchecked, experts believe typhoid has the potential of spreading like the polio virus
Typhoid vaccination drive extended till Dec 7 in Sindh
- The anti-typhoid vaccine has been administered to nine million children in Sindh during 12 days of the campaign, which began on November 18
- The Typhoid Conjugate Vaccination campaign has been extended till December 7 in Sindh to cover a higher percentage of children in the province
Enteric Fever Vaccine Candidate to Launch Phase 1 Study
- A London based biotechnology company has received Clinical Trial Authorization acceptance from the UK Medicines and Healthcare products Regulatory Agency to conduct a first-in-human Phase I trial for Entervax™, a vaccine candidate against typhoid
- Entervax is an oral, bivalent vaccine based on the Vaxonella® platform
- Prokarium said in a press release published on November 26, 2019, it anticipates dosing of the 1st subject to begin in the first quarter of 2020
WHO, Unicef and Pakistani experts declare new typhoid vaccine ‘very safe’
- About a dozen children had reportedly fainted in a private school after receiving TCV vaccination and were taken to a nearby private health facility and sent home after given first aid. However, panic gripped parents after this minor incident was highlighted by a section of the electronic and print media as a major health fiasco
- The World Health Organization (WHO), UNICEF and Pakistani child specialists and doctors said the newly-introduced vaccine was fully safe and would prevent children from nine months to 15 years of age from typhoid