New data from research on the disease burden of typhoid and ways to prevent, treat, and control the disease are crucial in the fight to take on typhoid. See the latest key publications or filter and search the full list of typhoid publications below.
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Identification of Genes Involved in Biogenesis of Outer Membrane Vesicles (OMVs) in Salmonella enterica Serovar Typhi
AUTHORS Jan Nevermann, Andrés Silva, Carolina Otero, Diego P. Oyarzún, Boris Barrera, Fernando Gil, Iván L. Calderón, and Juan A. Fuentes ABSTRACT Outer membrane vesicles (OMVs) are nano-sized proteoliposomes discharged ...
Read moreThe global burden of typhoid and paratyphoid fevers: a systematic analysis for the Global Burden of Disease Study 2017
AUTHORS GBD 2017 Typhoid and Paratyphoid Collaborators. BACKGROUND Efforts to quantify the global burden of enteric fever are valuable for understanding the health lost and the large-scale spatial distribution of ...
Read moreEvidence to Action: The 10th International Conference on Typhoid and Other Invasive Salmonelloses
AUTHORS Sarah Lindsay, Denise Garrett, and Duncan Steele ABSTRACT Typhoid and other invasive salmonelloses continue to cause a significant burden of disease, including morbidity, mortality, and financial cost, in low- ...
Read moreA Global Agenda for Typhoid Control-A Perspective from the Bill & Melinda Gates Foundation
AUTHORS Carey ME, Diaz ZI, Zaidi AKM, Steele AD. ABSTRACT Recognizing that enteric fever disproportionately affects the poorest and the most vulnerable communities that have limited access to improved sanitation, ...
Read moreProgress in Typhoid Fever Epidemiology
AUTHORS John A Crump ABSTRACT Salmonella enterica subspecies enterica serovar Typhi (Salmonella Typhi) is the cause of typhoid fever and a human host–restricted organism. Our understanding of the global burden ...
Read moreRevised Global Typhoid Vaccination Policy
AUTHORS Adwoa D Bentsi-Enchill and Joachim Hombach ABSTRACT Typhoid fever is a continuing public health problem in many low- and middle-income countries; however, routine vaccination as a recommended control strategy ...
Read moreOverview of the Typhoid Conjugate Vaccine Pipeline: Current Status and Future Plans
AUTHORS Sushant Sahastrabuddhe and Tarun Saluja ABSTRACT Typhoid fever remains a common and serious disease in populations that live in low- and middle-income countries. Treatment usually consists of antibiotics, but ...
Read moreCeftriaxone-resistant Salmonella Typhi Outbreak in Hyderabad City of Sindh, Pakistan: High Time for the Introduction of Typhoid Conjugate Vaccine
AUTHORS Mohammad Tahir Yousafzai, Farah Naz Qamar, Sadia Shakoor, Khalid Saleem, Heeramani Lohana, Sultan Karim, Aneeta Hotwani, Shahida Qureshi, Naveed Masood, Mudasir Rauf, Jamshed Ahmed Khanzada, Momin Kazi, and Rumina ...
Read moreMultidrug-resistant Nontyphoidal Salmonella Hotspots as Targets for Vaccine Use in Management of Infections in Endemic Settings
AUTHORS Samuel Kariuki, Cecilia Mbae, Robert Onsare, Susan M Kavai, Celestine Wairimu, Ronald Ngetich, Mohammad Ali, John Clemens, and Gordon Dougan Background Salmonella infections cause a disproportionately high number of ...
Read moreIntroduction of Typhoid Conjugate Vaccines in Africa and Asia
AUTHORS Kathleen M Neuzil, Andrew J Pollard, and Anthony A Marfin ABSTRACT Typhoid fever continues to be a major public health concern, particularly in many low- and middle-income countries. The ...
Read moreIntegrating Typhoid Fever Within the Sustainable Development Goals: Pragmatism or Utopia?
AUTHORS Zulfiqar A Bhutta ABSTRACT Several decades following the first estimates of the global burden of typhoidal salmonellosis (infections caused by Salmonella Typhi and Salmonella Paratyphi), this disorder remains a ...
Read moreTrends in antibiotic susceptibility of enteric fever isolates from South India, 2002–2013
AUTHORS Sangeeta Joshi, Ranjeeta Adhikary, Hosdurg Bhaskar Beena, Malavalli Venkatesh Bhavana, and Air Vice Mshl Rajvir Bhalwar (Retd) ABSTRACT Enteric fever is endemic in India. Trends in antibiotic resistance in ...
Read moreStructural and Physiological Exploration of Salmonella Typhi YfdX Uncovers Its Dual Function in Bacterial Antibiotic Stress and Virulence
AUTHORS Hye Seon Lee, Soohyun Lee, Jun-Seob Kim, Hae-Ran Lee, Ho-Chul Shin, Moo-Seung Lee, Kyeong Sik Jin, Cheol-Hee Kim, Bonsu Ku, Choong-Min Ryu, and Seung Jun Kim ABSTRACT YfdX is ...
Read moreMultidrug resistant enteric fever in South Asia: unmet medical needs and opportunities
AUTHORS Christopher M Parry, Isabela Ribeiro, Kamini Walia, Priscilla Rupali, Stephen Baker, Buddha Basnyat ABSTRACT Enteric fever (typhoid) is the commonest bacterial bloodstream infection in South Asia. It is caused ...
Read moreEpidemiological Profile and Antimicrobial Resistance Pattern of Enteric Fever in a Tertiary Care Hospital of North India – a Seven Year Ambispective Study
AUTHORS Anuradha Makkar, Shilpi Gupta, Inam Danish Khan, Rajiv Mohan Gupta, KS Rajmohan, Harleen Chopra, Manisha Gupta, Sachin Bansal, Bindu Poonia, Muqtadir Malik, Pragyan Swagatika Panda ABSTRACT Enteric-fever is a ...
Read moreMultiple Splenic Abscesses in a Case of Enteric Fever: Salvaging Spleen through Pigtail Drainage and Antibiotics is a Good Alternative Approach
AUTHORS Vijoy Kumar Jha and Tushar Vidhale ABSTRACT Splenic abscess is a rare complication of enteric fever in developing countries. This is seen mostly solitary rather than being multiple and ...
Read moreNotes from the Field: Typhoid Fever Outbreak — Harare, Zimbabwe, October 2017–February 2018
AUTHORS Hammad S. N’cho, Kudzai P.E. Masunda, Innocent Mukeredzi, Portia Manangazira, Emmaculate Govore, Clemence Duri, Rachael D. Aubert, Haley Martin, Elizabeth Gonese, Michael Vere, Beth A. Tippett Barr, Shirish Balachandra, ...
Read moreFive-year Audit of Infectious Diseases at a Tertiary Care Hospital in Karachi, Pakistan
AUTHORS Naseem Salahuddin, Muhammad Khalid, Naila Baig-Ansari, and Sundus Iftikhar ABSTRACT Purpose To estimate the burden of infectious diseases and the seasonality of mosquito-borne diseases seen at The Indus Hospital, ...
Read moreEmergence of Extensively Drug-Resistant Salmonella Typhi Infections Among Travelers to or from Pakistan – United States, 2016-2018
AUTHORS Kevin Chatham-Stephens, Felicita Medalla, Michael Hughes, Grace D. Appiah, Rachael D. Aubert, Hayat Caidi, Kristina M. Angelo, Allison T. Walker, Noël Hatley, Sofia Masani, June Nash, John Belko, Edward ...
Read moreSalmonella enterica serovar Typhi osteomyelitis in a young adult with sickle cell and thalassemia traits: A possible association
AUTHORS Stephanie Stephanie and Sarah A. Schmalzle ABSTRACT Salmonella osteomyelitis is known to occur in immunocompromised and sickle cell disease patients. It rarely occurs in other hosts. We present a ...
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