Since an outbreak of extensively drug resistant (XDR) typhoid, Pakistan has made great progress in typhoid prevention and control. In 2019, the country introduced typhoid conjugate vaccine (TCV), a highly ...
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Celebrating the 50th anniversary of the ever-evolving EPI
World Immunization Week, celebrated in the last week of April, is a global campaign that aims to highlight the importance of collective action to promote vaccination. In 2024, World Immunization ...
Read moreTyphoid burden, challenges, and the promise of typhoid conjugate vaccines
A recently published Nature Reviews Primer about typhoid discusses the epidemiology, disease burden, risk factors, genomics, and challenges, including multidrug resistance, diagnostics, and clinical presentation, as well as recent advances ...
Read moreA lack of diagnostic tools contributes to drug-resistant typhoid
Accurate diagnosis and treatment of typhoid is difficult in many low- and middle-income countries where the typhoid burden is highest. Blood culture-confirmed diagnosis, the gold standard, is expensive and requires ...
Read moreDrug resistant typhoid: what does it all mean?
Antimicrobial resistance, multidrug-resistant, antibiotic resistant, drug resistance – what does it all mean? Research shows that the technical terminology used to communicate the phenomenon of bacteria and viruses becoming non-susceptible ...
Read moreDrug-resistant typhoid: what we need to know
Drug resistance, an urgent global health challenge in recent years, was described by the World Health Organization (WHO) in 2019 as “one of the top ten global threats to public ...
Read moreThe need for typhoid conjugate vaccines in India
India is thought to have one of the highest burdens of typhoid in the world. Considering the emergence of drug resistance, climate change, and population movement, particularly during the COVID-19 ...
Read moreTransmission of drug-resistant typhoid is more local than global
Rising drug resistance, where currently available treatments for an illness are no longer effective, is a major public health concern. A myriad of research has documented increased rates of drug-resistant ...
Read moreNewly available genomic data highlights the need for urgent action to stop the emergence and spread of drug-resistant typhoid
For many high-income countries, typhoid is a disease of the past, thanks in part to municipal investments and improvements in safe water, sanitation, and hygiene infrastructure (WASH). However, one-third of ...
Read moreDrug resistance: It takes a global village
Why drug resistance should be on our radar Drug resistance occurs when bacteria, viruses, fungi, and parasites change over time and no longer respond to treatment. As a result, medicines ...
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