Diagnosing typhoid fever is challenging, and the scarcity of reliable burden data makes it difficult for decision-makers to understand and take action against typhoid. Typhoid symptoms—fever, diarrhea/constipation—are non-specific and common ...
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Ten years of surveillance finds a variable but persistently high typhoid burden in Kibera, Kenya
Typhoid remains a public health threat in many countries, particularly in Southeast Asia and sub-Saharan Africa. Understanding a country’s typhoid burden is often one of the first steps toward prevention ...
Read moreHow do water samples help identify typhoid burden?
Typhoid, caused by the bacterium Salmonella Typhi (S. Typhi), is notoriously difficult and expensive to diagnose. The gold standard diagnostic is blood culture confirmation, which is often unavailable at community ...
Read moreThe need for typhoid conjugate vaccines in India
India is thought to have one of the highest burdens of typhoid in the world. Considering the emergence of drug resistance, climate change, and population movement, particularly during the COVID-19 ...
Read moreA new diagnostic tool to understand typhoid burden
Typhoid remains extremely challenging to diagnose. The current gold standard diagnostic is laboratory confirmed blood culture. These tests are difficult to perform and require specialized laboratory skills and facilities. Many ...
Read moreUnpacking the burden of enteric fever in Bangladesh, Nepal, and Pakistan: Findings from SEAP Phase II
Typhoid conjugate vaccines (TCVs) can significantly reduce typhoid incidence in endemic communities. For policymakers in countries considering TCV introduction, accurate data are needed to inform the decision-making process. New data ...
Read moreUncovering the true typhoid burden in Bangladesh, Malawi, and Nepal
Typhoid causes more than 9 million cases and more than 110,000 deaths each year. Most of this burden is concentrated in areas of South and Southeast Asia and sub-Saharan Africa ...
Read moreAn app for Typhi genomes
Note: This blog originally appeared on the Nature Portfolio Microbiology Community. Typhoid fever is a serious enteric disease spread through food and water contaminated with Salmonella enterica serovar Typhi (S. Typhi). In 2017, ...
Read morePiecing together the typhoid surveillance puzzle
For decision-makers considering introduction of typhoid conjugate vaccines (TCV), data are key. National surveillance systems are the main mechanism for capturing data on typhoid cases but creating an effective typhoid ...
Read moreBeyond Morbidity and Mortality, Understanding the Burden of Enteric Fever in South Asia: New Results from Phase II of the Surveillance for Enteric Fever in Asia Project (SEAP)
Disease surveillance has long served as the foundation of public health, generating data to help guide policies and programs to effectively control and prevent a multitude of diseases. However, for ...
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