Typhoid fever is a serious enteric infection that can be cured through timely and accurate diagnosis and appropriate antibiotic treatment. However, this process is often difficult in low- and middle-income ...
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Author: Dr. John Crump, Centre for International Health, University of Otago
Typhoid conjugate vaccines, safe and effective in HIV-exposed uninfected children
While great progress has been made to reduce the burden of typhoid, there are more than 7 million cases per year and more than 93,000 annual deaths, according to recent ...
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A roadmap to tackling drug resistance in Africa
Drug resistance is a major global health challenge and it’s getting worse. A multitude of factors are contributing to the growth of drug resistance in general, and drug-resistant typhoid specifically ...
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Typhoid leaves its mark for generations
The significance of typhoid runs deep in my family. My mother grew up in the 1920s in British India—now Bangladesh—with 9 siblings. During that time, large families were common due ...
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Genomic analysis takes a closer look at drug-resistant typhoid in East Africa
Drug-resistant typhoid is a growing global health challenge. Antibiotics have been used to treat typhoid since the 1940s, but current antibiotics may not effectively treat typhoid for much longer given ...
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Connecting with the community: the success of Pakistan’s TCV campaign
Despite the proven success of vaccination programs to reduce disease burden and eliminate certain diseases, Pakistan continues to struggle with vaccine hesitancy. The latest typhoid conjugate vaccine (TCV) campaign, held ...
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Robust microplans are key to reaching every child in immunization campaigns
A successful immunization campaign depends on several critical elements to achieve the goal of reaching every child with a certain vaccine. Microplans are program documents, created prior to a campaign, ...
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TCV introduction projected to be cost saving in Bangladesh
Bangladesh has one of the highest incidences of typhoid fever per capita. It is estimated that there are more than three hundred cases of typhoid per one hundred thousand people ...
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As waters rise, so does risk of typhoid
In addition to improved water and sanitation, typhoid conjugate vaccines (TCVs) can prevent illness to at-risk communities during extreme weather events. Heavy rains and flash flooding in Kenya have displaced ...
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Uncovering the origins of H58 to stop drug-resistant typhoid in its tracks
Article published in Nature Portfolio Communications Biology, please see link here. Since the 1940s, antibiotics have been used to treat typhoid. With the rise of drug-resistant Salmonella Typhi (S. Typhi), ...
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