Dissemination of the mcr-1 colistin resistance gene


Herman Tse, Kwok-Yung Yuen


We read with interest the Article by Yi-Yun Liu and colleagues reporting the high rates of plasmid-mediated colistin resistance in Escherichia coli isolates from animal food sources in China. We share their concerns about potential widespread dissemination of the mcr-1 gene, which could lead to substantial morbidity and mortality associated with colistin failure in the clinical setting.


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