Clinical and Haematological Manifestations of Typhoid Fever in Children in Eastern Turkey


S Akbayram, M Parlak, M Dogan, G Karasin, HT Akbayram, K Karaman


Objective: Typhoid fever can involve various organs, leading to a wide range of presentations: from uncomplicated to complicated typhoid fever. The haematological changes are common in typhoid fever and include anaemia, leucopaenia, thrombocytopaenia and bleeding diathesis.

Methods: In this study, records of children and adolescents with typhoid fever aged ≥ 16 years, admitted to Yuzuncu Yil University Hospital between 2010 and 2014, were analysed retrospectively.

Results: The cases (56%) were admitted to our hospital in July and October. Major symptoms of patients were abdominal pain 24%, arthralgia 21%, and fever 11%. In our study, decreased mean platelet volume 31%, eosinopaenia 20%, abnormal platelet count 19%, anaemia 16%, leucocytosis 16% and eosinophilia 12% were the most common haematological findings in the children.

Conclusions: Typhoid fever is predominant in children at school age with a slight male predominance. Decreased mean platelet volume and abdominal pain might be useful as early diagnostic clues.


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