The Coalition against Typhoid’s activities are guided by a multi-stakeholder steering committee, currently chaired by Steve Luby, Professor of Infectious Diseases and Director of Research for Stanford’s Center for Innovation in Global Health. The committee meets quarterly and provides strategic direction and oversight to the Coalition.
Steve Luby, Stanford University
Steve Luby, MD is a physician and epidemiologist. He lived in Karachi, Pakistan for 5 years and Dhaka, Bangladesh for 8 years working with local researchers to broaden understanding of exposure pathways and disease burden of infectious diseases, including typhoid, and developing interventions to reduce that burden. In 2012 Dr. Luby joined Stanford University as a Professor of Infectious Diseases and Director of Research for Stanford’s Center for Innovation in Global Health. He is a Senior Fellow at Stanford’s Woods Institute for the Environment and at Stanford’s Freeman Spogli Institute for International Studies. In 2009 Dr. Luby was awarded the inaugural Oklahoma University International WaTER Prize in recognition of his contributions in the field of water supply and sanitation with a focus on the world’s poorest. Dr. Luby has mentored 41 scientists from low income countries to publish their initial first-authored manuscript in a peer reviewed international scientific journal; he has authored over 300 scientific articles.
Adwoa Bentsi-Enchill, World Health Organization
Dr. Adwoa Bentsi-Enchill is a Medical Officer in the Department of Immunization, Vaccines and Biologicals of the World Health Organization, Geneva where she currently leads WHO’s activities aimed at reviewing the evidence to support a revised global policy on typhoid vaccine use and to support national level decision-making for typhoid conjugate vaccine introduction in endemic countries. Dr Bentsi-Enchill’s previous work in WHO focused on immunization safety and she has over 14 years of experience in international health including technical support to immunization and other public health programmes in several countries across WHO’s six regions. Prior to joining WHO, Dr. Bentsi-Enchill worked as an epidemiologist in Health Canada (now Public Health Agency of Canada) from 1994 to 2000 and gained significant experience in public health programmes, field epidemiology, and various fields of immunization, including key roles in polio and acute flaccid paralysis surveillance, vaccine coverage monitoring, vaccine effectiveness studies and immunization safety.
Robert Breiman, Emory University
Dr. Breiman is Director of the Emory Global Health Institute (EGHI) where he oversees the strategy of engaging a wide array of disciplines and interests from undergraduate and graduate departments at Emory with the goal of integrated, innovative and impactful contributions from Emory towards addressing some of the planet’s most challenging problems affecting health in the 21st Century. EGHI has a highly interactive program with students and faculty with the aim of yielding leaders in global health science and programs. Dr. Breiman is the PI for the Rotavirus Immunization Program Evaluation in Kenya (RIPEK) project, a grant funded by Gavi, the Vaccine Alliance, the Scientific Advisory Process for Optimal Research on Typhoid (SAPORT) burden of disease project, funded by the Bill and Melinda Gates Foundation (BMGF), overseeing two large multicenter typhoid fever disease burden projects in sub-Saharan Africa and South Asia. He is also the PI for a large multi-center study to evaluate the pneumococcal genome over time to assess whether and how pneumococcal immunization programs have led to changes in pneumococci potentially resulting in changes in vaccine effectiveness, and is the Co-PI for a recently-awarded Bill and Melinda Gates Foundation-funded program called the Child Health and Mortality Prevention Surveillance (CHAMPS) Network. The CHAMPS program is a new global health surveillance network aimed at characterizing and preventing childhood mortality in Sub-Saharan Africa and South Asia.
Before joining Emory, Dr. Breiman was at the Centers for Disease Control and Prevention (CDC) for 26 years, most recently, based at CDC-Kenya from 2004-2013. Before moving to Kenya, Dr. Breiman was Director of the Health Systems and Infectious Diseases Division and Head, Programme on Infectious Diseases and Vaccine Sciences at the International Center for Diarrheal Disease Research in Dhaka, Bangladesh (ICDDR,B) from 2000-2004. He was previously the Director of the National Vaccine Program Office, reporting to the DHHS Assistant Secretary for Health from 1995-2000 and was the Chief of the Epidemiology Section of the Respiratory Diseases Branch from 1989-1995. He is Board Certified in Internal Medicine and in Infectious Diseases, a Fellow of the Infectious Diseases Society of America, and a member of the American Society of Epidemiology, the American Society of Tropical Medicine and Hygiene (for which he serves as Chair of the Pneumonia and TB scientific committee), and the American Society of Microbiology. Dr. Breiman is author or co-author of >340 peer reviewed original scientific articles, perspectives, and chapters.
John Crump, University of Otago
John Crump is McKinlay Professor of Global Health and Co-Director, Centre for International Health, University of Otago, Dunedin; Adjunct Professor of Medicine, Pathology, and Global Health at Duke University; and a Guest Researcher with the US Centers for Disease Control and Prevention. He graduated from the University of Otago Medical School in 1993 and trained as both an internist in infectious diseases and as a pathologist in medical microbiology, training at Christchurch Hospital, New Zealand; the Royal Free Hospital, London; the Canberra Hospital, Australia; Duke University Medical Center; and with the US Centers for Disease Control and Prevention. He is a Fellow of the Royal Australasian College of Physicians, a Fellow of the Royal College of Pathologists of Australasia, a Fellow of the Royal College of Physicians of the United Kingdom, and a diplomate of the London School of Hygiene and Tropical Medicine. His main interests are in the prevention, diagnosis, and treatment of infectious diseases in developing countries, with particular focus on febrile illness; invasive bacterial diseases especially the salmonelloses; bacterial zoonoses; HIV; tuberculosis; and enteric infections.
Melita Gordon, University of Liverpool
Melita Gordon MA MD FRCP DTM&H is a gastroenterologist and clinical scientist, living in Blantyre, Malawi. She trained in internal medicine in Oxford, Zambia, and Belfast, and in Gastroenterology in Sheffield and Liverpool. She has researched invasive Salmonella disease in Malawi for 19 years, first as a Wellcome Trust Clinical Research Fellow, then during a UKCRC Senior Clinical Lectureship, and currently as Professor of Gastroenterology in the Institute of Infection and Global Health in the University of Liverpool. In 2011 she was awarded the British Society of Gastroenterology’s Sir Francis Avery Jones Research Medal, and in 2012 the Shire SAGE first prize for Excellence in Gastroenterology. Her research encompasses clinical epidemiology and transmission modelling, clinical disease pathogenesis, host peripheral and mucosal cellular and molecular inflammatory response, bacterial phylogenomics. She is deputy director of a Wellcome Trust Clinical PhD Programme and academic lead of a Univerity of Malawi and Liverpool joint PhD registration programme, both developing training young researchers working in low-income settings. She also leads a World Gastroenterology Organization International Training Centre for gastroenterology and GI endoscopy.
Eric Mintz, Centers for Disease Control and Prevention
Dr. Eric Mintz obtained his medical degree from the State University of New York in 1984, completed an internal medicine residency at Harlem Hospital in 1987, and received a Masters in Public Health from Columbia University in 1989. That year he joined the Centers for Disease Control and Prevention, where he has worked on approaches to prevent waterborne and foodborne diseases in the Americas, Africa and Asia. Dr. Mintz has authored or co-authored over 150 scientific publications on topics including typhoid and paratyphoid fever, cholera, dysentery, and new technologies to make safe drinking water, safe sanitation and better hygiene more accessible, affordable, and sustainable in developing countries.
Christine Moe, Emory University
Dr. Moe is the Eugene J. Gangarosa Professor of Safe Water and Sanitation in the Rollins School of Public Health and the Director of the Center for Global Safe Water at Emory University. Her research focuses primarily on the environmental transmission of infectious agents, in particular, foodborne and waterborne diseases. Her field research in Bangladesh, Bolivia, Cambodia, China, El Salvador, Ghana, Honduras, India, Kenya, Mozambique, the Philippines, Rwanda, Uganda and the United States includes studies of diarrheal diseases, dry sanitation systems, fecal contamination in low-income urban environments, water quality in distribution systems, water, sanitation and hygiene in healthcare facilities in low-resource settings, and environmental contamination of vegetable crops. Dr. Moe served on the US Environmental Protection Agency Science Advisory Board and chaired a National Research Council Committee to advise USAID on Grand Challenges in International Development. She has been a consultant for the World Health Organization and the Bill and Melinda Gates Foundation. She has also served on the Water Science and Technology Board of the National Research Council and the Research Advisory Council for the American Water Works Research Foundation. She has received the World Bank Development Marketplace Infrastructure award and the NSF Food Safety Leadership award. Dr. Moe has a BA in Biology from Swarthmore College and MS and PhD in Environmental Sciences from the University of North Carolina at Chapel Hill.
Kathleen Neuzil, University of Maryland School of Medicine
Dr. Kathleen Neuzil is the project director of the Typhoid Vaccine Acceleration Consortium. She is a globally recognized vaccinologist with proficiency ranging from epidemiology, international field trials and vaccine policy, to partnerships with emerging manufacturers and direct experience with Gavi processes, World Health Organization (WHO) policy, and prequalification (PQ). She has led successful multi-year, multi-site, efforts in global health, informing vaccine policy recommendations and catalyzing introductions. She brings a fresh perspective and objective approach necessary to mobilize the field and move typhoid conjugate vaccines (TCVs) forward.
Samir Saha, Child Health Research Foundation
Dr. Samir Saha is the Professor and Head of the Department of Microbiology and the Executive Director of The Child Health Research Foundation at the Bangladesh Institute of Child Health, Dhaka Shishu Hospital in Dhaka, Bangladesh. Dr. Saha is also an associate of the Department of International Health at Johns Hopkins University and adjunct scientist at International Centre for Diarrhoeal and Research, Bangladesh (ICDDR,B). Dr. Saha is currently a member of the National Committee for Immunization Policies of the Government of Bangladesh. He is also a member of WHO Technical Working Group for Vaccine Preventable Diseases surveillance network and Pneumococcus Awareness Council of Experts (PACE).
Dr. Saha has published more than 100 papers in peer-reviewed journals, mostly relating to childhood pneumonia and meningitis. He is now conducting several multi-site and multi-country research projects on infectious disease supported by different international funding organizations. In addition to studies on child health, Dr. Saha is also the Principal Investigator of the multi-site and multi-country project on Aetiology of Neonatal Infection in South Asia (ANISA) project, supported by the Bill and Melinda Gates Foundation. The ANISA project is currently being conducted in three South Asian countries and is a major international effort to determine the root causes of community-based neonatal and maternal infection, and develop evidence-based strategies to protect children and mothers in the subcontinent. Dr. Saha earned his MSc. from The University of Dhaka in Bangladesh in 1983, and his PhD from the Institute of Medical Sciences of Banaras Hindu University, Varanasi, India, in 1989.