Barriers to Typhoid Vaccine Uptake

1. Limited disease burden & vaccine health impact data
2. Lack of consensus on vaccine choice (conjugate vs. non-conjugate)
3. No established vaccination strategies regarding who, where or how to vaccinate
4. No committed donor financing

   

5. Lack of focused communications and advocacy for raising country awareness, adoption & fundraising
6. Diagnostic tool limitations which hinders the ability to generate credible disease burden data (and identify high risk groups)
7. The cost-driven preference for inexpensive treatment over vaccines
8. Other potential challenges:

• Paratyphi burden
• Lack of WHO prequalified vaccines
• Country political will
• Managing typhoid as a communicable disease rather than within the immunization system
• Current focus on Hib, pneumococcal, and rotavirus vaccine introduction in GAVI countries